Originally Posted by Hajo Flettner
When one talks about toxicology the state of the substance and the means of ingestion are critical. somewhere else the matter of thujone came up and one simply will never come upon enough pure thujone to cause health troubles. You'd literally have to a pound of sage in a sitting to hurt yourself. The same is true of nicotine in that you never simply injest pure nicotine and the effects of nicotine toxicity simply don't occure in places where tobacco is consumed as food. In the end it simply makes no sense to talk about the sonsumption of pure nicotine and LD 50 tests because that is not how it's consumed.
true but then the question arises of how much is really absorbed in the different ways (since things like dip and chew allow the nicotine to go in to the blood faster and i would assume all of the ways normally used to "consume" tobacco/nicotine allow it to enter the blood faster
im not arguing the fact that its hard/next to impossible to consume enough to cause a lethal dose but in the mg/kg relationship to be lethal it is very low comparatively